Lifespan

In his book, Lifespan, David Sinclair has proposed a radical new theory of aging, suggesting that the aging hallmarks are symptoms of epigenetic changes that occur over time, but that the original genetic code remains very much intact.

If we can reset the code, we can slow, stop and even reverse aging.

David Sinclair is a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School, where he and his colleagues study sirtuins—protein-modifying enzymes that respond to changing NAD+ levels and to caloric restriction—as well as chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration, cancer, and cellular reprogramming.

Sinclair has suggested that aging is a disease—and that we may soon have the tools to put it into remission—and he has called for greater international attention to the social, economic and political risks and benefits of a world in which billions of people can live much longer and much healthier lives.

David doesn’t give health recommendations or endorse brands, but he does share his personal supplementation which is closely related to his research.

David’s Daily Supplement Regimen:

• Resveratrol – 1 gram daily – mornings with yogurt
• NMN – 1 gram daily – mornings
• Metformin (prescription drug in the US) – 1 gram daily – 0.5 grams in the morning & 0.5 grams at night – except on days when exercising
• Statin – a cholesterol lowering prescription drug taken since his early 20s due to family history of cardiovascular disease
• Aspirin – 83mg daily
• Vitamins – Aims to get majority from diet, but has mentioned supplementing the following:
  • Vitamin D3
  • Vitamin K2
  • Alpha Lipoic Acid
  • Coenzyme Q10
  • Quercetin